Congratulations to successful PhD Defense Daniëlle Verschoor

On February 10, 2023 Daniëlle Verschoor, student of the Cutting Edge Microscopy (CEM) program under the supervision of Prof. Stephan von Gunten, has successfully defended her PhD thesis with the title: “Granulocytes, fragile but resistant. Unraveling the treatment resistance of granulocytes.”

Her PhD project focused on the treatment resistant of inflammatory granulocyte, both neutrophils and eosinophils. Freshly isolated human peripheral granulocytes were stimulated with pro-inflammatory cytokines as GM-CSF and/or IL-5 followed by treatments as intravenous immunoglobulins, anti-siglec-7/9 or glucocorticoids to investigate their cell survival or death and to investigate possible mechanism involved in this response. In her project microscopy was used to characterize subsets of cells and analyze/visualize cell death. This all to unravel the mechanism responsible for their resistance to these treatments.