PhD Defense M. Golomingi

Murielle Koni-Kepo Golomingi student at the PhD program Cutting Edge Microscopy (CEM) under the supervision of Prof. Dr. Verena Schröder, will give her PhD Defense on March 15, 2023 at 14.00 at the ARTORG Center for Biomedical Engineering Research.
Title: “Interactions between the complement system and blood coagulation: a potential role of complement components and activation during haemostasis"

Haemostasis is a crucial process by which the body stops bleeding. It is achieved by the formation of a platelet plug, which is strengthened by the formation of a fibrin mech through the coagulation cascade. In case of pathological clotting, for instance in arterial thrombosis, the interactions of the complement system and the coagulation cascades is known to aggravate the development of the pathology. Whether those interactions play a relevant role during non-pathological haemostasis is however not yet completely understood. The aim of this study was to investigate the potential role of complement components and activation during haemostasis.